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Land-use change alters the habitats available to wildlife. Conservation research examines how the loss of these habitats affects biodiversity.
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Biodiversity in a fragmented world
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Patch-seq combined with volumetric electron microscopy has revealed cell-type-specific inhibitory connectivity profiles across transcriptomically-defined neuron populations, providing a wiring diagram of subtype selective perisomatic targeting (Gamlin et al., 2025), as illustrated in Fig. 2a. These connectivity motifs align with the projection neuron-type specific output dynamics recently characterised in motor cortex corticothalamic circuits (Li et al., 2026), as shown in Fig. 3b-e, with inhibitory inputs analysed across all cortical sections.
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Prime editing technology has advanced genome editing by enabling precise nucleotide changes without double-strand breaks. We employed prime editing to correct a mutation in the CFTR gene in bronchial epithelial cells to explore therapeutic applications for cystic fibrosis (Anzalone et al., 2019)
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Journal
Integrated analysis of multimodal single-cell data
Hao et al.
Cell
Volume 184, Issue 13, Pages 3573-3587.e29
2021
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CRISPR/Cas9 therapeutics: progress and prospects
Li et al.
Signal Transduction and Targeted Therapy
Volume 8, Issue 1
2023
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Journal
Comparison of methods and resources for cell-cell comm...
Dimitrov et al.
Nature Communications
Volume 13, Issue 1
2022
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Journal
Deciphering spatial domains from spatially resolved transcriptomics with an adaptive graph attention auto-encoder
Kangning Dong, Shihua Zhang
Nature Communications
Volume 4, Issue 11
2022
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The time-dependent Schrödinger equation dictates the evolution of the wave function in a quantum-mechanical system. It provides a deterministic description of the quantum state's progression over time. This formulation is foundational to quantum mechanics, enabling precise predictions of particle dynamics at the atomic scale.
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Microplastics, tiny plastic particles less than 5mm in size, have become a significant concern in marine environments. Originating from various sources such as cosmetics, clothing fibers, and degraded plastic waste, these particles are widespread across oceans. Studies indicate that microplastics can cause physical harm and chemical toxicity to marine organisms, disrupting ecosystems. This study examines the physiological, behavioral, and reproductive effects of microplastics on marine life to better understand their impact and support conservation efforts.
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Understanding random variables is crucial in statistical analysis. Let X be a continuous random variable that follows a normal distribution with a mean of 0 andard deviation of tribution with mean rete random variable oisson distribution with rate λ=Research assistant
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Cognitive behavioral therapy has been shown to be an effective treatment for individuals with anxiety disorders, with meta-analyses indicating moderate to large
This approach typically involves identifying and challenging maladaptive thought patterns, learning coping strategies for managing anxiety symptoms, and gradually
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